Introduction of the function of superfine pulverizer in the processing technology of traditional Chinese medicine

Release time：2023-1-9 Number of hits：1746

The ultra-fine pulverizer can effectively pulverize any fibrous, high toughness and high hardness materials, and is especially suitable for traditional Chinese medicine cell wall breaking and other materials that aim to improve the bioavailability of drugs and cannot reach the required fineness with conventional methods.

In addition to biological pharmacy, food and cosmetics, it is also widely used in various industries related to powder application, such as building materials (preparation of ultra-fine water slag, fly ash, etc.), chemical industry, metallurgy, environmental protection (making bricks with garbage powder, etc.), and electronics (slurry, graphite emulsion, etc.).

The original medicinal materials can be crushed with a particle size of 150 from the traditional crushing method by using an ultra-fine pulverizer μ m-200 μ M increased to 5 μ m-10 μ m. The plant powder can reach 95% wall breaking level. The temperature of the ultra-fine pulverizer can be controlled at medium temperature, low temperature and ultra-low temperature. Medicinal materials with different physical and chemical properties can be used. And the wall breaking machine is suitable for different medicinal materials. Ultrafine powder can fully retain the active ingredients in the crude drug. The dissolution of the active ingredients is faster, the release is faster, and the absorption process in the body is more direct and faster. The drug utilization rate is greatly improved.

The ultra-fine powder recorded in the pharmacopoeia means that the wall breaking rate of 95% passing the No. 9 sieve (200 meshes) and 99% passing the No. 8 sieve (150 meshes) is about 10%. Ultrafine powder usually refers to crushing Chinese herbal medicine to 300-500 meshes, with a comprehensive wall breaking rate of about 90% or higher. The specific mesh number corresponding to the wall breaking rate is related to the cell size with traditional Chinese medicine.

At present, the application of the ultra-fine pulverizer in the preparation of traditional Chinese medicine is mainly based on the fact that the effective components of traditional Chinese medicine are stored in various cell tissues of plants and are difficult to be extracted due to the barrier of the thin chest wall. The cell wall is broken, and the effective ingredients are fully exposed, which can be directly leached. From the point of view that plant cells are crushed, it is also called cell level grinder.

Through the superfine pulverization of the original medicinal materials, the micro powder medicinal materials that are more suitable for the absorption and utilization of the body can be obtained, thus greatly improving the bioavailability and therapeutic effect of the original medicinal materials; The research and application of this technology in the field of traditional Chinese medicine has laid a foundation for the improvement of the level of traditional Chinese medicine preparations and the introduction of Chinese patent medicine to the world.